请问英语中nonetheless的用法在实际中怎末用？句子中？

  一般用在句子开头，如：
Nonetheless, solutions are out there。 For example, you can set a goal to reduce the number of helpdesk complaints 20% over the course of the year。
  
Moreover, the author conclude without solid evidence that it is applying Luxess everyday morning that lead to the improvement of appearance and feeling of skin。
   Nonetheless,without solid evidence, this causality is still full of loopholes。 。